Isifo sikaPeyronie

isifo sepipi

Isifo sikaPeyronie yisifo esixhuma izicubu esihilela ukukhula kwamapuleti anemicu ezicutshini ezithambile zepipi .Ngokukhethekile, amafomu wesicubu esibomvu ku-tunica albuginea, umgogodla wesicubu ozungeze i- corpora cavernosa, obangela ubuhlungu, ukugobeka okungavamile, ukungasebenzi kahle kwe-erectile, ukuqaqanjelwa, ukulahlekelwa yibhande kanye nokunciphisa. [1]

Kulinganiselwa ukuthi kuthinta cishe amadoda ayi-10%.Isimo siba ngokuvame kakhulu ngeminyaka.

Izimpawu nezimpawu

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Isibonelo sokukhubazeka kwepipi kusuka eceleni

Izinga elithile lokugobeka lobudoda lithathwa njengelivamile, njengoba amadoda amaningi ezalwa enalesi simo sobungozi, esivame ukubizwa ngokuthi ukugobeka kokuzalwa.Lesi sifo singadala ubuhlungu; izilonda eziqinile, ezinkulu, ezifana nentambo (izicubu ezibomvu ezaziwa ngokuthi "amapuleti"); noma ukugobeka kwendoda ngokungajwayelekile lapho imile ngenxa yokuvuvukala okungapheli kwe- tunica albuginea (CITA).

Izimbangela

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Imbangela yesifo sikaPeyronie ayaziwa.Noma kunjalo, kungenzeka ukuthi kungenxa yokwakheka kocwecwe ngaphakathi kwepenisi ngenxa yokuhlukumezeka okuphindaphindayo noma ukulimala ngesikhathi sokuya ocansini noma komzimba. [2]

Izici ezinobungozi zibandakanya isifo sikashukela, isivumelwano sikaDupuytren, i- plantar fibromatosis, ukuhlukunyezwa kwe-penile, ukubhema, ukuphuza ngokweqile , ukuthambekela kofuzo, kanye nefa laseYurophu. [3] [4]

Ukuxilongwa

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Le ultrasound iveza izingxenye ezihlukanisiwe zepenisi ezindaweni ezahlukahlukene esigulini esinesifo sikaPeyronie.Isithombe esiphezulu sikhombisa ukwakheka komzimba okujwayelekile kanti isithombe esingezansi sikhombisa izicubu ezibomvu kwi- tunica albuginea (umthondo).Izicubu ezibomvu zihlala endaweni futhi zibhekele ukukhubazeka okuphawuleka kwesifo sikaPeyronie (ukugobeka nokuncipha).

Udokotela we-urologist angakwazi ukuxilonga lesi sifo futhi asikisele ukwelashwa.I-ultrasound inganikeza ubufakazi obuqand 'ikhanda besifo sikaPeyronie, esinquma ukuphuma kwesisu noma okunye ukuphazamiseka. [5]

Ukwelashwa

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Imithi nezithasiselo

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Izindlela eziningi zokwelapha ngomlomo sezifundwe kepha imiphumela kuze kube manje ixutshiwe. [7]Abanye babheka ukusetshenziswa kwezindlela ezingezona ezokuhlinzwa njengokuphikisana ". [8]

Ukwengezwa kukaVitamin E sekufundwe amashumi eminyaka, futhi impumelelo ethile ibikiwe ezivivinyweni ezindala kepha leyo mpumelelo ayiphindwanga ngokuthembekile ezifundweni ezinkulu, ezintsha. [9]

Ukusetshenziswa kwe- Interferon-alpha-2b ezigabeni zokuqala zalesi sifo sekufundwe kepha kusukela ngo-2007 ukusebenza kwaso bekungabazeka. [10]

I-Collagenase clostridium histolyticum kubikwa ukuthi izosiza ngokudiliza i-collagen eyeqile kupipi.Kwavunyelwa ukwelashwa kwesifo sikaPeyronie yi-FDA ngo-2013.

Ukwelashwa ngokomzimba namadivayisi

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Kunobufakazi obulinganiselayo bokuthi i-penile traction therapy iyindlela ebekezeleleke kahle, yokwelashwa okuhlasela kancane, kepha kunokungaqiniseki ngobude besikhathi sokululeka ngosuku nangendlela yokwelashwa, futhi inkambo yokwelashwa inzima. [11]

Ukwelashwa Kwe-Shockwave Okugxile

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Ukwelashwa okugxilwe ngaphandle kwe-shockwave kuyindlela yokwelashwa engeyona ehlaselayo ebandakanya ukudlulisa izingqimba ze-acoustic nge-plaque, ezingayidiliza ngaphezulu kwezikhathi eziyisithupha kuya kweziyishumi nambili. [12] [13]Ukwelashwa kusebenza kakhulu emadodeni anamaPeyronie amancane.

Ukuhlinzwa

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Ukuhlinzwa, okufana "nokusebenza kweNesbit" (okuqanjwe ngoReed M. Nesbit (1898-1979), udokotela wase-American urologist e- University of Michigan ), [2] kuthathwa njengesixazululo sokugcina futhi kufanele kwenziwe kuphela ngomchamo onekhono kakhulu odokotela abahlinzayo abanolwazi ngamasu akhethekile wokuhlinza okulungisa.Ukufakwa kwe-penile kungahle kufaneleke ezimweni ezisezingeni eliphakeme. [14]

I-Epidemiology

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Kulinganiselwa ukuthi kuthinta cishe amadoda ayi-10%.Isimo siba ngokuvame kakhulu ngeminyaka. [15]Iminyaka yobudala ekuqaleni kwesifo yiminyaka engama-55-60. [2]

Umlando

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Isimo sichazwe okokuqala ngo-1561 ngokuxhumana phakathi kuka- Andreas Vesalius noGabriele Falloppio ngokuhlukile nguGabriele Falloppio.Lesi simo sibizwa ngoFrançois Gigot de la Peyronie, owasichaza ngo-1743.

Izinkomba

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  1. "Peyronie's disease and erectile dysfunction: Current understanding and future direction". Indian Journal of Urology 22 (3): 246–50. doi:10.4103/0970-1591.27633. 
  2. 2.0 2.1 2.2 The management of Peyronie's disease. January 2004. Ralph, D. J.; Minhas, S. (January 2004). Cite error: Invalid <ref> tag; name "pmid14690485" defined multiple times with different content
  3. Hatzimouratidisa, Konstantinos; Eardley, Ian (2012). "EAU guidelines on penile curvature". European Urology 62 (3): 543–552. doi:10.1016/j.eururo.2012.05.040. PMID 22658761. 
  4. Abern, Michael R.; Levine, Laurence A. (2009). "Peyronie's disease: evaluation and review of nonsurgical therapy". The Scientific World Journal 27 (9): 665–675. doi:10.1100/tsw.2009.92. PMID 19649505. 
  5. Colour Doppler and duplex ultrasound assessment of Peyronie's disease in impotent men. May 1993. 
  6. Cite error: Invalid <ref> tag; no text was provided for refs named FernandesSouza2018
  7. Levine LA (October 2003). Review of current nonsurgical management of Peyronie's disease. 
  8. A critical analysis of nonsurgical treatment of Peyronie's disease. June 2006. 
  9. Oral therapy for Peyronie's disease. October 2002. 
  10. Pharmacological Management of Peyronie's Disease. 
  11. "Penile traction therapy and Peyronie's disease: a state of art review of the current literature". Ther Adv Urol. 5 (2): 59–65. February 2013. doi:10.1177/1756287212454932. PMC 3547530. PMID 23372611. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=3547530. 
  12. https://www.nice.org.uk/guidance/ipg29/documents/overview-of-extracorporeal-shockwave-therapy-for-peyronies-disease2
  13. https://edclinics.co.uk/peyronies-disease/
  14. "Surgical approaches for advanced Peyronie's disease patients". International Journal of Impotence Research 15 (Suppl 5): S121–4. October 2003. doi:10.1038/sj.ijir.3901085. PMID 14551588. 
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